EPT 富马酸盐（N-乙基-N-丙基色胺）

EPT Fumarate (N-ethyl-N-propyltryptamine) – Scientific Product Description

General Features

EPT Fumarate is a research chemical from the tryptamine class, characterized by its unique N-ethyl-N-propyl substitution pattern. This compound exhibits structural similarities to known tryptamines such as DMT and MET, but is distinguished by specific pharmacodynamic properties.

Core specifications:

• Chemical Purity:  >98% (verified by HPLC-MS)

• Molecular Stability:  Excellent stability due to fumarate salt formation

• 溶解度：  Freely soluble in water and organic solvents

• 储存条件：  Long-term stability at -20°C in inert gas atmosphere

科学应用

1. 神经药理学研究：

   • Serotonergic Receptor Interactions (5-HT1A/2A/2C)

   • Monoamine oxidase inhibition studies

   • Neurotransmitter release mechanisms

2. 代谢研究：

   • Liver microsome metabolism profile

   • Cytochrome P450 interaction analysis

3. 比较药理学：

   • Structure-activity relationships versus other N,N-dialkyltryptamines

   • Dose-response characterization in vitro

实验指南

Dosage Ranges for In Vitro Studies:

Safety protocols:

• Always work under controlled laboratory conditions

• Personal protective equipment (lab coat, nitrile gloves, safety glasses) required

• Use only in a fume hood when handling solvents

稳定性数据

Documented Stability:

• Room temperature: <72 hours in solution

• Refrigerated (4°C): stable for 1 week

• Frozen (-20°C): stable for >6 months

Recommended Storage:

• Primary packaging: Amber glass vials with PTFE closure

• Secondary packaging: Vacuum sealed with silica gel pack

• Storage conditions: -20°C under argon atmosphere

Analytical Certification

每批均附带：

1. Extensive HPLC analysis (UV/VIS detection)

2. Mass spectrometry confirmation (LC-MS/MS)

3. 残留溶剂分析

4. Water content determination (Karl Fischer)

Legal Status & Ethics

Dutch Regulations:

• Currently not included in the Opium Act

• Valid under general medicinal products legislation for research chemicals

• Mandatory registration for scientific institutions

Ethical Guidelines:

• For non-clinical research use only

• Prohibited for human or animal administration

• Mandatory ethical review for academic research

常见问题

Q1: How does EPT compare to structurally similar tryptamines?
A: The ethyl-propyl substitution exhibits unique pharmacokinetic properties, particularly in:

• Lipophilicity profile (logP value: 2.1)

• Protein binding capacity (88-92%)

• Brain barrier penetration (0.65 ratio to DMT)

Q2: What are the detection options in standard drug screenings?
A: EPT is not recognized by conventional immunoassays, but is detectable via:

• GC-MS (characteristic fragmentation at m/z 130, 144)

• LC-QTOF (precision measurement of molecular mass)

Q3: Are there any known interactions with medications?
A: Theoretical interactions are possible with:

• MAO inhibitors (potentiation effect)

• SSRIs (competitive inhibition)

• Antipsychotics (receptor competition)

Q4: What is the recommended waste disposal?
A: Follow the hazardous waste protocol:

• Neutralize with dilute hydrochloric acid (0.1M)

• Absorb with suitable material (e.g. vermiculite)

• Dispose of as hazardous chemical waste (EC number: 404-860-3)

科学参考文献

Important literature references:

1. Nichols, D. E. (2018). “Structure-activity relationships of tryptamines”

2. Brandt 等人（2020 年）。“新型精神活性物质的分析表征”

3. 欧盟早期预警系统（2023年）。“新型色胺衍生物的风险评估”

This product is intended solely for authorized scientific research by qualified personnel. All information is provided without any implied warranty. Users are responsible for complying with local regulations.