GM Fluoride Sachet 1g – Advanced Research Fluoridation Agent
Product definition
GM-Fluor is a highly reactive fluorination agent for organic synthesis, specially developed for advanced pharmaceutical research & materials science .
✔ 1gr high purity powder
✔ ≥99% chemical purity
✔ Special stabilizers for safer use
✔ GMP certified production
实验室报告(COA)摘要
*Batch #GMF-0427-NL | Tested by FluorChem Labs*
✔ 99.2% purity (XRD analysis)
✔ <0.1% heavy metals 电感耦合等离子体发射光谱仪
✔ Moisture content <0.5% (Karl Fischer)
✔ Reactivity Index :A+级
应用领域
1. Pharmaceutical Synthesis
Selective fluoridation of aromatic compounds
Prodrug activation studies
2. Materials science
Fluoropolymer synthesis
Surface modification
3.分析化学
Isotope labeling studies (¹⁸F/¹⁹F)
HPLC retention optimization
使用协议
Standard Fluoridation
Dissolve 无水 DMF 溶液(50mg/ml)
Add under argon atmosphere
Reaction temperature :40-60℃
Duration : 2-4 hours
安全
• Always work under inert gas
• Double gloves (nitrile + neoprene)
• Eye/face protection 强制的
优势
✓ Higher yield than traditional fluorinating agents
✓ Milder reaction conditions possible
✓ Broad substrate spectrum
✓ Minimal byproduct formation
缺点
⚠ Extremely reactive with water
⚠ Requires specialized equipment
⚠ Short shelf life after opening (6 months)
⚠ High cost compared to alternatives
常见问题 (FAQ)
Q: How does GM Fluorine compare to DAST?
| 范围 | GM Fluorine | DAST |
|---|---|---|
| Reactivity | ★★★★ | ★★★ |
| 安全 | ★★★ | ★★ |
| Costs | €€€€ | €€ |
Q: Can I use this for PET scan precursor synthesis?
一个: 是的 – Suitable for ¹⁸F labelling (provided appropriate facilities are available)
Q: What is the storage method?
一个: Vacuum packed at -20°C under argon
问:如果发生皮肤接触怎么办?
答:立即用 polyethylene glycol 400 + seek medical attention
减少伤害协议
• 保持 calcium gluconate gel
available • Do not use metal tools
• pH neutralization protocol for waste
Disclaimer: For use by certified chemists only. Not for amateur chemistry.
🔬Complete safety file? Email to safety@[company name].nl
Caution: Requires specially ventilated laboratory (fume hood class III).
Research bundle
When ordering >5g:
✓ Free fluoridation protocol book
✓ Access to our reaction database
LEGAL WARNING: This product is classified as hazardous materials under the Hazardous Substances Act . Special permits are required for purchase and use.
Recommended Reaction Conditions
| Substrate type | 温度 | Time | Yield |
|---|---|---|---|
| Aromatics | 50°C | 3h | 85-92% |
| Alcohols | 40°C | 2 hours | 78-85% |
| Carboxylic acids | 60°C | 4am | 90-95% |
| 5 星级 | 53 | 53% |
| 四星级 | 39 | 39% |
| 3 星 | 8 | 8% |
| 2 星 | 0% | |
| 1 星 | 0% |
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