Pastilles DMXE 40 mg (désoxyméthoxétamine)

DMXE (Deoxymethoxetamine) 40mg Pellets – Scientific Product Documentation

🔬Chemical Specifications

DMXE (2′-Oxo-PCE-d10) is a research chemical belonging to the arylcyclohexylamine class, structurally related to MXE (methoxetamine) and ketamine. These pellets are formulated for precise scientific research.

Core parameters:

• IUPAC name : 2-(3,4-diméthylphényl)-2-(éthylamino)cyclohexanone

• Molecular formula : C₁₆H₂₃NO

• Molecular weight : 245.36 g/mol

• Pureté : ≥98% (GC-MS analysis)

• Shape : Round, 4mm diameter pellets

• Color : Light beige to white

• Solubilité : 15 mg/ml in water (at 25°C)

🧪Applications scientifiques

1. Recherche neuropharmacologique :

   • Études d'antagonisme des récepteurs NMDA

   • Sigma-1 receptor interaction assays

2. Behavioral Neuroscience :

   • Effects on learning behavior in laboratory animals

   • Dose-dependent dissociative effects

3. Psychopharmacologie :

   • Comparative studies with related dissociatives

   • Research into neuroplastic effects

⚖️Protocoles de recherche recommandés

Experimental guidelines:

*Note: Non-linear pharmacokinetics above 25 mg/kg*

⚠️Safety Profile & Risk Management

1. Toxicological data :

   • LD₅₀ (rat, oral): 320 mg/kg

   • NOAEL: 5 mg/kg/day (7-day study)

2. Side effect spectrum :

   • <10 mg: Subtle behavioral effects

   • 10-30 mg: Motor incoordination

   • 30 mg: Potential respiratory depression

3. Critical Interactions :

   • Dangerous : Opioids, GABA-ergics

   • Risky : Stimulants, MAO inhibitors

📊Quality Control & Analytical Data

• HPLC purity : 98.5% (C18 column, 70:30 H₂O:MeCN)

• Uniformity : ±5% weight deviation (n=20 pellets)

• Disintegration time : <15 minutes (in simultaneous gastric juice)

• Données de stabilité :

  • Shelf life: 24 months at 15-25°C

  • Moisture sensitivity: <0.5% weight gain (93% RH)

❓Frequently Asked Research Questions

Q1: What is the mechanism of action?
A: Primary NMDA receptor antagonism with secondary dopamine reuptake inhibition.

Q2: How does the potency compare to ketamine?
A: ~0.6x the potency of ketamine but a longer half-life (4-6 hours).

Q3: Are there neurotoxic risks?
A: Olney’s lesions were not observed at <50 mg/kg (rat study).

Q4: What is the optimal storage method?
A: In the original packaging at 15-25°C, protected from moisture.

📌Research limitations

• Limited data on chronic administration

• Unknown effects on glutamate transmission

• Variable biotransformation between species

🔍Conclusion for Researchers

DMXE 40mg pellets offer a standardized formulation for precise dissociative research, with consistent dose delivery and good stability. The pellet form facilitates quantitative administration in animal studies.

Scientific disclaimer: This product is intended solely for in vitro research and authorized preclinical studies. Not for human use. All experiments must comply with applicable ethical guidelines and local regulations. Please be aware of the special status of psychoactive research substances in your jurisdiction.