{"id":23655,"date":"2025-04-13T17:40:11","date_gmt":"2025-04-13T17:40:11","guid":{"rendered":"https:\/\/globalsourcechemicals.com\/?post_type=product&p=23655"},"modified":"2025-10-03T07:20:20","modified_gmt":"2025-10-03T07:20:20","slug":"idra-21-10-mg-pelete","status":"publish","type":"product","link":"https:\/\/globalsourcechemicals.com\/sl\/trgovina\/idra-21\/idra-21-10-mg-pelete\/","title":{"rendered":"IDRA-21 10 mg peleti"},"content":{"rendered":"

IDRA-21 10 mg peleti \u2013 znanstveni opis in uporabni\u0161ki priro\u010dnik<\/span><\/span><\/strong><\/h3>\n

Opis izdelka<\/span><\/span><\/strong><\/h4>\n

IDRA-21 (10 mg pelete)<\/span><\/span><\/strong> \u00a0je potencial\u00a0 <\/span><\/span>Potenciator AMPA receptorjev<\/span><\/span><\/strong> \u00a0ki pripadajo razredu\u00a0 <\/span><\/span>nootropne in nevroprotektivne raziskovalne kemikalije<\/span><\/span><\/strong> Deluje tako, da okrepi signalizacijo v mo\u017eganih, ki jo povzro\u010da glutamat, kar lahko vodi do izbolj\u0161ane kognitivne funkcije, nevroplasti\u010dnosti in potencialno nevrookrevanja.<\/span><\/span><\/p>\n

Ti peleti so\u00a0 <\/span><\/span>visoko \u010dist (\u226598%)<\/span><\/span><\/strong> , standardizirano odmerjeno in namenjeno izklju\u010dno za\u00a0 <\/span><\/span>znanstvene raziskave in predklini\u010dne \u0161tudije<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

\n

Uporaba in aplikacije<\/span><\/span><\/strong><\/h3>\n

Zdravilo IDRA-21 se preu\u010duje glede njegovih mo\u017enih u\u010dinkov na:<\/span><\/span><\/p>\n

    \n
  1. \n

    Kognitivno izbolj\u0161anje<\/span><\/span><\/strong> \u00a0\u2013 Lahko pove\u010da budnost, sposobnost u\u010denja in utrjevanje spomina.<\/span><\/span><\/p>\n<\/li>\n

  2. \n

    Nevroprotekcija<\/span><\/span><\/strong> \u00a0\u2013 Potencialni za\u0161\u010ditni u\u010dinek pri nevrodegenerativnih boleznih (npr. Alzheimerjeva bolezen, mo\u017eganska kap).<\/span><\/span><\/p>\n<\/li>\n

  3. \n

    Nevrolo\u0161ko okrevanje<\/span><\/span><\/strong> \u00a0\u2013 Lahko spodbuja sinapti\u010dno plasti\u010dnost po po\u0161kodbi mo\u017eganov.<\/span><\/span><\/p>\n<\/li>\n

  4. \n

    Znanstvene raziskave<\/span><\/span><\/strong> \u00a0\u2013 \u0160tudija modulacije receptorjev AMPA in signalizacije glutamata.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

    \u26a0\u00a0Ni odobreno za uporabo v humani ali veterinarski medicini \u2013 samo za in vitro in kontrolirane predklini\u010dne \u0161tudije.<\/span><\/span><\/strong><\/p>\n

    \n

    Navodila za odmerjanje in varnost<\/span><\/span><\/strong><\/h3>\n
      \n
    • \n

      Odmerjanje v raziskavi (in vitro\/predklini\u010dno): <\/span><\/span><\/strong>\u00a05\u201320 mg\/kg<\/span><\/span><\/strong> \u00a0(odvisno od modela).<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Raztopina peletov:<\/span><\/span><\/strong> \u00a0Lahko se raztopi v\u00a0 <\/span><\/span>destilirana voda ali DMSO<\/span><\/span><\/strong> \u00a0za poskuse.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Administracija:<\/span><\/span><\/strong> \u00a0Oralno (\u017eivalski modeli) ali neposredno v celi\u010dnih kulturah.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Pogostost:<\/span><\/span><\/strong> \u00a0Enkratni odmerek za akutni u\u010dinek; dolgoro\u010dne \u0161tudije zahtevajo skrbno spremljanje.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

      \ud83d\udea8\u00a0Opomba:<\/span><\/span><\/strong><\/p>\n

        \n
      • \n

        Brez uporabe pri ljudeh<\/span><\/span><\/strong> \u00a0\u2013 Ni podatkov o varnosti za uporabo pri ljudeh.<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Visoki odmerki lahko povzro\u010dijo nevroekscitotoksi\u010dnost.<\/span><\/span><\/strong><\/p>\n<\/li>\n

      • \n

        Izogibajte se kombinaciji z drugimi modulatorji glutamata.<\/span><\/span><\/strong><\/p>\n<\/li>\n<\/ul>\n

        \n

        Slabosti in tveganja<\/span><\/span><\/strong><\/h3>\n
          \n
        • \n

          Prekomerna stimulacija nevronov<\/span><\/span><\/strong> \u00a0(nevarnost eksitotoksi\u010dnosti v primeru prevelikega odmerjanja).<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Mo\u017ena tesnoba ali vznemirjenost<\/span><\/span><\/strong> \u00a0pri ob\u010dutljivih modelih.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Omejeni dolgoro\u010dni podatki<\/span><\/span><\/strong> \u00a0glede tolerance in ne\u017eelenih u\u010dinkov.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Ni primerno za kroni\u010dno uporabo<\/span><\/span><\/strong> \u00a0brez obse\u017enih \u0161tudij toksi\u010dnosti.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

          \n

          Pogosto zastavljena vpra\u0161anja (FAQs)<\/span><\/span><\/strong><\/h3>\n

          1. Ali je IDRA-21 zakonit na Nizozemskem?<\/span><\/span><\/strong><\/h4>\n

          Da, ampak samo za\u00a0 <\/span><\/span>znanstvene raziskave<\/span><\/span><\/strong> Ne spada pod zakon o opiju, vendar tudi ni odobren kot zdravilo.<\/span><\/span><\/p>\n

          2. Kako natan\u010dno deluje IDRA-21?<\/span><\/span><\/strong><\/h4>\n

          To\u00a0 <\/span><\/span>okrepi odziv receptorja AMPA<\/span><\/span><\/strong> , zaradi \u010desar je signalizacija glutamata dalj\u0161a in intenzivnej\u0161a. To lahko vodi do izbolj\u0161ane sinapti\u010dne komunikacije.<\/span><\/span><\/p>\n

          3. Ali lahko IDRA-21 primerjamo z drugimi nootropiki?<\/span><\/span><\/strong><\/h4>\n

          Ima edinstven mehanizem delovanja, vendar\u00a0 <\/span><\/span>podobne tar\u010de kot racetami ali ampakini<\/span><\/span><\/strong> \u00a0(npr. Sunifiram).<\/span><\/span><\/p>\n

          4. Ali obstajajo kak\u0161ne znane interakcije?<\/span><\/span><\/strong><\/h4>\n
            \n
          • \n

            Antagonisti NMDA<\/span><\/span><\/strong> \u00a0(npr. memantin) \u2013 mo\u017eni ne\u017eeleni u\u010dinki.<\/span><\/span><\/p>\n<\/li>\n

          • \n

            GABAergi\u010dna sredstva<\/span><\/span><\/strong> \u00a0(npr. benzodiazepini) \u2013 Lahko zmanj\u0161ajo anksioliti\u010dne u\u010dinke.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

            \n

            Laboratorijsko poro\u010dilo in nadzor kakovosti<\/span><\/span><\/strong><\/h3>\n
              \n
            • \n

              HPLC analiza: <\/span><\/span><\/strong>\u00a0\u010cistost \u226598%<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Brez zaznavnih ostankov te\u017ekih kovin ali topil<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Homogena formulacija peletov<\/span><\/span><\/strong> \u00a0za dosledno odmerjanje.<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Certificiranje serije<\/span><\/span><\/strong> \u00a0na voljo raziskovalnim ustanovam.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

              \n

              Priporo\u010deni raziskovalni scenariji<\/span><\/span><\/strong><\/h3>\n
                \n
              1. \n

                Kognitivne \u0161tudije<\/span><\/span><\/strong> \u00a0\u2013 Vplivi na spomin in u\u010denje pri \u017eivalskih modelih.<\/span><\/span><\/p>\n<\/li>\n

              2. \n

                Nevroprotektivne raziskave<\/span><\/span><\/strong> \u00a0\u2013 Potencialna vloga pri ishemi\u010dni po\u0161kodbi (modeli kapi).<\/span><\/span><\/p>\n<\/li>\n

              3. \n

                Elektrofiziologija<\/span><\/span><\/strong> \u00a0\u2013 Meritve odziva receptorjev AMPA v nevronskih kulturah.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                \ud83d\udd2c\u00a0Samo za nadzorovano laboratorijsko uporabo \u2013 Ni za rekreativno uporabo!<\/span><\/span><\/strong><\/p>\n

                ","protected":false},"excerpt":{"rendered":"

                Lastnosti peletov IDRA-21<\/span><\/span><\/h3>\n

                Sinonim<\/span><\/span><\/strong> 7-kloro-3-metil-3,4-dihidro-2H-1,2,4-benzotiadiazin 1,1-dioksid <\/span><\/span>
                \nCAS <\/span><\/span><\/strong> \u0160tevilka<\/span><\/span><\/strong> : 22503-72-6 <\/span><\/span>
                \nFormula<\/span><\/span><\/strong> C8H9ClN2O2S <\/span><\/span>
                \nMolska masa<\/span><\/span><\/strong> : 232,6 g\/mol <\/span><\/span>
                \n\u010cistost<\/span><\/span><\/strong> : >97%<\/span><\/span><\/p>","protected":false},"featured_media":27900,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[548,549,330,324],"product_tag":[326],"class_list":{"0":"post-23655","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-idra-21","7":"product_cat-idra-21-pellets","8":"product_cat-nootropics","9":"product_cat-pellets-for-pellet","10":"product_tag-nl","12":"first","13":"instock","14":"taxable","15":"shipping-taxable","16":"purchasable","17":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/product\/23655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/comments?post=23655"}],"version-history":[{"count":5,"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/product\/23655\/revisions"}],"predecessor-version":[{"id":28058,"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/product\/23655\/revisions\/28058"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/media\/27900"}],"wp:attachment":[{"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/media?parent=23655"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/product_brand?post=23655"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/product_cat?post=23655"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sl\/wp-json\/wp\/v2\/product_tag?post=23655"}],"curies":[{"name":"delovni list","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}