{"id":23878,"date":"2025-04-13T17:40:36","date_gmt":"2025-04-13T17:40:36","guid":{"rendered":"https:\/\/globalsourcechemicals.com\/?post_type=product&p=23878"},"modified":"2025-10-02T23:08:35","modified_gmt":"2025-10-02T23:08:35","slug":"hxe-hydroxetamin","status":"publish","type":"product","link":"https:\/\/globalsourcechemicals.com\/sk\/obchod\/arylcyklohexylamin\/hxe-hydroxetamin\/","title":{"rendered":"HXE (hydroxetam\u00edn)"},"content":{"rendered":"

HXE (hydroxetam\u00edn) \u2013 inovat\u00edvny arylcyklohexylam\u00edn pre neurovedn\u00fd v\u00fdskum<\/span><\/span><\/strong><\/h1>\n

N\u00e1zov produktu:<\/span><\/span><\/strong> HXE (hydroxetam\u00edn) <\/span><\/span>
\nCel\u00e9 meno:<\/span><\/span><\/strong> 3-hydroxy-2-oxo-PCE <\/span><\/span>
\nChemick\u00e1 trieda:<\/span><\/span><\/strong> Arylcyklohexylam\u00edny <\/span><\/span>
\nMolekul\u00e1rny vzorec:<\/span><\/span><\/strong> C13H17NO2 <\/span><\/span>
\nMolekulov\u00e1 hmotnos\u0165:<\/span><\/span><\/strong> 219,28 g\/mol <\/span><\/span>
\nVzh\u013ead:<\/span><\/span><\/strong> Jemn\u00fd kry\u0161talick\u00fd pr\u00e1\u0161ok (biely a\u017e svetlob\u00e9\u017eov\u00fd) <\/span><\/span>
\n\u010cistota:<\/span><\/span><\/strong> \u2265 98% (overen\u00e9 pomocou HPLC a NMR) <\/span><\/span>
\nPou\u017eitie:<\/span><\/span><\/strong> Len na laborat\u00f3rny a farmakologick\u00fd v\u00fdskum <\/span><\/span>
\nBaliace jednotky:<\/span><\/span><\/strong> 250 mg \/ 500 mg \/ 1 g<\/span><\/span><\/p>\n

\n

\ud83d\udd2c \u010co je HXE (hydroxetam\u00edn)?<\/span><\/span><\/strong><\/h2>\n

HXE je <\/span><\/span>nov\u00e1 arylcyklohexylam\u00ednov\u00e1 zl\u00fa\u010denina<\/span><\/span><\/strong> a \u0161truktur\u00e1lny anal\u00f3g O-PCE (eticyklid\u00edn). Je zn\u00e1my svojou aktivitou ako <\/span><\/span>Antagonista NMDA receptora<\/span><\/span><\/strong> , podobne ako disocia\u010dn\u00e9 \u010dinidl\u00e1, ako je ketam\u00edn alebo MXE. HXE sa vyzna\u010duje pr\u00edtomnos\u0165ou <\/span><\/span>hydroxylov\u00e1 skupina<\/span><\/span><\/strong> , \u010do mu dod\u00e1va jedine\u010dn\u00e9 farmakokinetick\u00e9 a farmakodynamick\u00e9 vlastnosti.<\/span><\/span><\/p>\n

HXE sa pou\u017e\u00edva v\u00fdlu\u010dne na <\/span><\/span>v\u00fdskum neurovedy, receptorov a metabolizmu<\/span><\/span><\/strong> v kontrolovan\u00fdch laborat\u00f3ri\u00e1ch.<\/span><\/span><\/p>\n

\n

\u2705 Aplik\u00e1cie a vyu\u017eitie vo v\u00fdskume<\/span><\/span><\/strong><\/h2>\n
    \n
  • V\u00e4zba na receptor (NMDA, sigma, mGluR):<\/span><\/span><\/strong> Anal\u00fdza antagonistick\u00fdch vlastnost\u00ed<\/span><\/span><\/li>\n
  • \u0160t\u00fadia \u0161truktur\u00e1lnej aktivity (SAR):<\/span><\/span><\/strong> Porovnanie v r\u00e1mci arylcyklohexylam\u00ednovej skupiny<\/span><\/span><\/li>\n
  • Neurochemick\u00fd behavior\u00e1lny v\u00fdskum<\/span><\/span><\/strong> (in vitro\/in vivo s etick\u00fdm schv\u00e1len\u00edm)<\/span><\/span><\/li>\n
  • Metabolick\u00e9 \u0161t\u00fadie:<\/span><\/span><\/strong> Anal\u00fdza metabolick\u00fdch dr\u00e1h a produktov rozkladu<\/span><\/span><\/li>\n
  • Porovn\u00e1vacia anal\u00fdza disocia\u010dn\u00e9ho profilu<\/span><\/span><\/strong><\/li>\n<\/ul>\n

    D\u00f4le\u017eit\u00e9:<\/span><\/span><\/strong> HXE je <\/span><\/span>nie je ur\u010den\u00e9 na \u013eudsk\u00fa spotrebu<\/span><\/span><\/strong> a mal by sa pou\u017e\u00edva\u0165 iba pod <\/span><\/span>laborat\u00f3rne podmienky<\/span><\/span><\/strong> s primeran\u00fdmi bezpe\u010dnostn\u00fdmi opatreniami.<\/span><\/span><\/p><\/blockquote>\n

    \n

    \u26a0\ufe0f Mo\u017en\u00e9 nev\u00fdhody a rizik\u00e1<\/span><\/span><\/strong><\/h2>\n
      \n
    • Nezn\u00e1my bezpe\u010dnostn\u00fd profil:<\/span><\/span><\/strong> K dispoz\u00edcii s\u00fa obmedzen\u00e9 toxikologick\u00e9 \u00fadaje<\/span><\/span><\/li>\n
    • Potenci\u00e1lne neurotoxick\u00fd pri zneu\u017eit\u00ed<\/span><\/span><\/strong><\/li>\n
    • \u0160truktur\u00e1lny vz\u0165ah s kontrolovan\u00fdmi l\u00e1tkami<\/span><\/span><\/strong> \u2192 pr\u00e1vne rizik\u00e1<\/span><\/span><\/li>\n
    • Nie je vhodn\u00e9 na dlhodob\u00e9 skladovanie v priestoroch s v\u00fdparmi<\/span><\/span><\/strong><\/li>\n
    • Nie je schv\u00e1len\u00fd liek ani doplnok stravy<\/span><\/span><\/strong><\/li>\n<\/ul>\n
      \n

      \ud83e\uddea Laborat\u00f3rne inform\u00e1cie<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n\n\n\n
      Charakteristick\u00fd<\/span><\/span><\/th>\n\u0160pecifik\u00e1cia<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
      Formul\u00e1r<\/span><\/span><\/td>\nKry\u0161talick\u00fd pr\u00e1\u0161ok<\/span><\/span><\/td>\n<\/tr>\n
      Farba<\/span><\/span><\/td>\nBiela a\u017e svetlob\u00e9\u017eov\u00e1<\/span><\/span><\/td>\n<\/tr>\n
      \u010cistota<\/span><\/span><\/td>\n\u2265 98% (analyzovan\u00e9 HPLC)<\/span><\/span><\/td>\n<\/tr>\n
      Rozpustnos\u0165<\/span><\/span><\/td>\n\u013dahko rozpustn\u00fd v etanole, DMSO<\/span><\/span><\/td>\n<\/tr>\n
      Rady pre skladovanie<\/span><\/span><\/td>\nSuch\u00e9, tmav\u00e9, chladn\u00e9 (2\u20138 \u00b0C)<\/span><\/span><\/td>\n<\/tr>\n
      \u010c\u00edslo \u0161ar\u017ee<\/span><\/span><\/td>\nPozri obal<\/span><\/span><\/td>\n<\/tr>\n
      Certifik\u00e1cia pravosti k dispoz\u00edcii<\/span><\/span><\/td>\n\u00c1no, na po\u017eiadanie za d\u00e1vku<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
      \n

      \ud83d\udca1 Odpor\u00fa\u010dan\u00e9 pr\u00edpady pou\u017eitia<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n
      Scen\u00e1r<\/span><\/span><\/th>\nOdpor\u00fa\u010dan\u00fd postup<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
      Anal\u00fdza v\u00e4zby receptorov NMDA<\/span><\/span><\/td>\nZrie\u010fte v etanole a d\u00e1vkujte pomocou mikrosk\u00famaviek<\/span><\/span><\/td>\n<\/tr>\n
      \u0160t\u00fadie neurotoxicity in vitro<\/span><\/span><\/td>\nVystavenie buniek roztoku rozp\u00fa\u0161\u0165adla<\/span><\/span><\/td>\n<\/tr>\n
      Chromatografia (LC-MS\/GC-MS)<\/span><\/span><\/td>\nRie\u0161i\u0165, filtrova\u0165 a analyzova\u0165<\/span><\/span><\/td>\n<\/tr>\n
      Referen\u010dn\u00e1 vzorka<\/span><\/span><\/td>\nZahrn\u00fa\u0165 do analytick\u00e9ho \u0161kolenia alebo syntetick\u00e9ho projektu<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
      \n

      \u2753 \u010casto kladen\u00e9 ot\u00e1zky (FAQ)<\/span><\/span><\/strong><\/h2>\n

      1. Je HXE v mojej krajine leg\u00e1lne?<\/span><\/span><\/strong>
      \n Status HXE sa v jednotliv\u00fdch regi\u00f3noch zna\u010dne l\u00ed\u0161i. V niektor\u00fdch krajin\u00e1ch spad\u00e1 pod analogick\u00e9 z\u00e1kony. Pred pou\u017eit\u00edm alebo dovozom si overte miestne predpisy.<\/span><\/span><\/p>\n

      2. M\u00f4\u017ee sa HXE pou\u017ei\u0165 ako n\u00e1hrada ketam\u00ednu? <\/span><\/span><\/strong>
      \nNie.<\/span><\/span><\/strong> HXE je ur\u010den\u00fd len na v\u00fdskumn\u00e9 \u00fa\u010dely. Ak\u00e9ko\u013evek rekrea\u010dn\u00e9 alebo lek\u00e1rske pou\u017eitie je nebezpe\u010dn\u00e9 a nez\u00e1konn\u00e9.<\/span><\/span><\/p>\n

      3. Je HXE stabiln\u00fd pri izbovej teplote?<\/span><\/span><\/strong>
      \n \u00c1no, kr\u00e1tkodobo, ale <\/span><\/span>dlhodob\u00e9 skladovanie<\/span><\/span><\/strong> vy\u017eaduje such\u00e9 a chladn\u00e9 prostredie (2\u20138 \u00b0C).<\/span><\/span><\/p>\n

      4. M\u00f4\u017eem ho kombinova\u0165 s in\u00fdmi l\u00e1tkami vo v\u00fdskume?<\/span><\/span><\/strong>
      \n \u00c1no, za predpokladu, \u017ee kombin\u00e1cia je racion\u00e1lna a bezpe\u010dn\u00e1 v r\u00e1mci va\u0161ej v\u00fdskumnej met\u00f3dy.<\/span><\/span><\/p>\n

      5. Ako z\u00edskam certifik\u00e1t o anal\u00fdze?<\/span><\/span><\/strong>
      \n A <\/span><\/span>COA (Certifik\u00e1t anal\u00fdzy)<\/span><\/span><\/strong> je k dispoz\u00edcii na po\u017eiadanie od dod\u00e1vate\u013ea na z\u00e1klade \u010d\u00edsla \u0161ar\u017ee.<\/span><\/span><\/p>\n

      \n

      \ud83d\udce6 Preh\u013ead produktu<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n\n\n\n
      Funkcia<\/span><\/span><\/th>\n\u0160pecifik\u00e1cia<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
      N\u00e1zov produktu<\/span><\/span><\/td>\nHXE (hydroxetam\u00edn)<\/span><\/span><\/td>\n<\/tr>\n
      Aplik\u00e1cia<\/span><\/span><\/td>\nFarmakologick\u00fd a chemick\u00fd v\u00fdskum<\/span><\/span><\/td>\n<\/tr>\n
      Balenie<\/span><\/span><\/td>\n250 mg \/ 500 mg \/ 1 g<\/span><\/span><\/td>\n<\/tr>\n
      Formul\u00e1r<\/span><\/span><\/td>\nKry\u0161talick\u00fd pr\u00e1\u0161ok<\/span><\/span><\/td>\n<\/tr>\n
      \u010cistota<\/span><\/span><\/td>\n\u2265 98%<\/span><\/span><\/td>\n<\/tr>\n
      Skladovanie<\/span><\/span><\/td>\nChladn\u00e9, such\u00e9, tmav\u00e9<\/span><\/span><\/td>\n<\/tr>\n
      Pr\u00e1vne postavenie<\/span><\/span><\/td>\nZ\u00e1vis\u00ed od regi\u00f3nu<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

       <\/p>","protected":false},"excerpt":{"rendered":"

      Vlastnosti HXE<\/span><\/span><\/span><\/span><\/h3>\n

      Synonymum: <\/span><\/span><\/span><\/span><\/strong> 3'-hydroxy-2-oxo-PCE<\/span><\/span><\/span><\/span><\/b> , <\/span><\/span><\/span><\/span>O-desmetylmetoxetam\u00edn<\/span><\/span><\/span><\/span><\/b> , <\/span><\/span><\/span><\/span>HXE <\/span><\/span><\/span><\/span><\/b>
      \n\u010c\u00edslo CAS:<\/span><\/span><\/span><\/span><\/strong> 1620054-73-0 <\/span><\/span><\/span><\/span>
      \nVzorec:<\/span><\/span><\/span><\/span><\/strong> C14H19NO2 <\/span><\/span><\/span><\/span>
      \nMol\u00e1rna hmotnos\u0165:<\/span><\/span><\/span><\/span><\/strong> 233,311 g mol\u22121 <\/span><\/span><\/span><\/span>
      \n\u010cistota:<\/span><\/span><\/span><\/span><\/strong> >99%<\/span><\/span><\/span><\/span><\/p>","protected":false},"featured_media":27898,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[71,492],"product_tag":[326],"class_list":{"0":"post-23878","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-arylcyclohexylamine","7":"product_cat-hxe","8":"product_tag-nl","10":"first","11":"instock","12":"taxable","13":"shipping-taxable","14":"purchasable","15":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product\/23878","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/comments?post=23878"}],"version-history":[{"count":5,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product\/23878\/revisions"}],"predecessor-version":[{"id":28039,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product\/23878\/revisions\/28039"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/media\/27898"}],"wp:attachment":[{"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/media?parent=23878"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product_brand?post=23878"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product_cat?post=23878"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product_tag?post=23878"}],"curies":[{"name":"pracovn\u00fd list","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}