{"id":23587,"date":"2025-04-13T17:40:01","date_gmt":"2025-04-13T17:40:01","guid":{"rendered":"https:\/\/globalsourcechemicals.com\/?post_type=product&p=23587"},"modified":"2025-10-03T07:27:28","modified_gmt":"2025-10-03T07:27:28","slug":"2-3-fea-40-mg-120-mg-pelety","status":"publish","type":"product","link":"https:\/\/globalsourcechemicals.com\/sk\/obchod\/takmer-zakazane\/2-3-fea-40-mg-120-mg-pelety\/","title":{"rendered":"2\/3-FEA 40 MG\/120MG pelety"},"content":{"rendered":"

2\/3-FEA 40 MG \/ 120 MG pelety \u2013 vedeck\u00fd popis produktu<\/span><\/span><\/strong><\/h3>\n

V\u0161eobecn\u00e9 inform\u00e1cie<\/span><\/span><\/strong><\/h4>\n

2\/3-FEA (2-flu\u00f3retamfetam\u00edn\/3-flu\u00f3retamfetam\u00edn)<\/span><\/span><\/strong> \u00a0je\u00a0 <\/span><\/span>v\u00fdskumn\u00e1 zl\u00fa\u010denina z rodiny deriv\u00e1tov flu\u00f3ramfetam\u00ednu<\/span><\/span><\/strong> , s potenci\u00e1lnymi stimula\u010dn\u00fdmi a empatog\u00e9nnymi vlastnos\u0165ami. Tieto pelety obsahuj\u00fa\u00a0 <\/span><\/span>presne d\u00e1vkovan\u00e1 kombin\u00e1cia 40 mg 2-FEA a 120 mg 3-FEA<\/span><\/span><\/strong> , optimalizovan\u00e9 pre\u00a0 <\/span><\/span>predklinick\u00e9 \u0161t\u00fadie<\/span><\/span><\/strong> \u00a0alebo farmakodynamick\u00e9 interakcie.<\/span><\/span><\/p>\n

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Aplik\u00e1cie a oblasti v\u00fdskumu<\/span><\/span><\/strong><\/h3>\n

V\u010faka svojej jedine\u010dnej du\u00e1lnej \u0161trukt\u00fare sa 2\/3-FEA sk\u00fama pre:<\/span><\/span><\/p>\n

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  1. \n

    V\u00fdskum neurotransmiterov<\/span><\/span><\/strong> \u00a0\u2013 \u00da\u010dinky na uvo\u013e\u0148ovanie dopam\u00ednu, norepinefr\u00ednu a seroton\u00ednu.<\/span><\/span><\/p>\n<\/li>\n

  2. \n

    Behavior\u00e1lna farmakol\u00f3gia<\/span><\/span><\/strong> \u00a0\u2013 Vplyvy na pohybov\u00fa aktivitu a syst\u00e9my odme\u0148ovania v zvierac\u00edch modeloch.<\/span><\/span><\/p>\n<\/li>\n

  3. \n

    Stimula\u010dn\u00e9 \u00fa\u010dinky<\/span><\/span><\/strong> \u00a0\u2013 Porovn\u00e1vacie \u0161t\u00fadie s klasick\u00fdmi amfetam\u00ednmi.<\/span><\/span><\/p>\n<\/li>\n

  4. \n

    \u0160t\u00fadie afinity k receptorom<\/span><\/span><\/strong> \u00a0\u2013 Sk\u00famanie selektivity pre transport\u00e9ry monoam\u00ednov.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

    \u26a0\u00a0Nie je ur\u010den\u00e9 na pou\u017eitie u \u013eud\u00ed \u2013 Len na testovanie in vitro a na kontrolovan\u00fdch zvierat\u00e1ch.<\/span><\/span><\/strong><\/p>\n

    \n

    D\u00e1vkovanie a sp\u00f4sob pod\u00e1vania<\/span><\/span><\/strong><\/h3>\n

    Predklinick\u00e9 pokyny:<\/span><\/span><\/strong><\/h4>\n
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      N\u00edzky akt\u00edvny dosah:<\/span><\/span><\/strong> \u00a00,5 \u2013 2 mg\/kg (pre jemn\u00e9 \u00fa\u010dinky)<\/span><\/span><\/p>\n<\/li>\n

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      Stredn\u00fd rozsah:<\/span><\/span><\/strong> \u00a02 \u2013 5 mg\/kg (zjasn\u00e9 behavior\u00e1lne \u00fa\u010dinky)<\/span><\/span><\/p>\n<\/li>\n

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      Vysok\u00fd rozsah:<\/span><\/span><\/strong> \u00a05 \u2013 10 mg\/kg (len pre \u0161t\u00fadie ak\u00fatnej toxicity)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

      Rozpustnos\u0165:<\/span><\/span><\/strong><\/h4>\n
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        \u013dahko rozpustn\u00fd v\u00a0 <\/span><\/span>fyziologick\u00fd roztok<\/span><\/span><\/strong> \u00a0(na injekciu)<\/span><\/span><\/p>\n<\/li>\n

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        Mierne rozpustn\u00fd v\u00a0 <\/span><\/span>DMSO<\/span><\/span><\/strong> \u00a0(pre pr\u00e1cu in vitro)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

        Sp\u00f4soby podania:<\/span><\/span><\/strong><\/h4>\n
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          Or\u00e1lne (zvieracie modely)<\/span><\/span><\/p>\n<\/li>\n

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          Intraperitone\u00e1lne (pre r\u00fdchlej\u0161iu absorpciu)<\/span><\/span><\/p>\n<\/li>\n

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          Testy transport\u00e9rov in vitro<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

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          Bezpe\u010dnostn\u00e9 aspekty a rizik\u00e1<\/span><\/span><\/strong><\/h3>\n

          Ak\u00fatne rizik\u00e1:<\/span><\/span><\/strong><\/h4>\n
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            Kardiovaskul\u00e1rny stres<\/span><\/span><\/strong> \u00a0(zv\u00fd\u0161en\u00fd srdcov\u00fd tep\/krvn\u00fd tlak)<\/span><\/span><\/p>\n<\/li>\n

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            \u00a0Vysok\u00e1 d\u00e1vka <\/span>hypertermia<\/span><\/strong><\/span><\/p>\n<\/li>\n

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            Seroton\u00ednov\u00fd syndr\u00f3m<\/span><\/span><\/strong> \u00a0v kombin\u00e1cii s inhib\u00edtormi MAO<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

            Chronick\u00e9 rizik\u00e1:<\/span><\/span><\/strong><\/h4>\n
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              Neurotoxicita<\/span><\/span><\/strong> \u00a0(pri dlhodobom u\u017e\u00edvan\u00ed vysok\u00fdch d\u00e1vok)<\/span><\/span><\/p>\n<\/li>\n

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              Dopaminergn\u00e1 depl\u00e9cia<\/span><\/span><\/strong><\/p>\n<\/li>\n

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              Behavior\u00e1lna senzibiliz\u00e1cia<\/span><\/span><\/strong><\/p>\n<\/li>\n<\/ul>\n

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              Laborat\u00f3rna anal\u00fdza a kontrola kvality<\/span><\/span><\/strong><\/h3>\n

              Analytick\u00e9 \u0161pecifik\u00e1cie:<\/span><\/span><\/strong><\/h4>\n
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                Potvrdenie HPLC-MS<\/span><\/span><\/strong> \u00a0zlo\u017eenie<\/span><\/span><\/p>\n<\/li>\n

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                Pomer 1:3 (2-FEA:3-FEA)<\/span><\/span><\/strong> \u00a0s odch\u00fdlkou <5%<\/span><\/span><\/p>\n<\/li>\n

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                \u017diadne detekovate\u013en\u00e9 izom\u00e9rne ne\u010distoty<\/span><\/span><\/strong><\/p>\n<\/li>\n

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                Mikrobiologick\u00e1 \u010distota:<\/span><\/span><\/strong> \u00a0<100 CFU\/g<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                \u00dadaje o stabilite:<\/span><\/span><\/strong><\/h4>\n
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                  Trvanlivos\u0165:<\/span><\/span><\/strong> \u00a024 mesiacov pri 4 \u00b0C<\/span><\/span><\/p>\n<\/li>\n

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                  Fotosenzitivita:<\/span><\/span><\/strong> \u00a0Skladujte v jant\u00e1rovom obale<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

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                  Odpor\u00fa\u010dan\u00e9 v\u00fdskumn\u00e9 protokoly<\/span><\/span><\/strong><\/h3>\n
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                  1. \n

                    \u0160t\u00fadie mikrodial\u00fdzy<\/span><\/span><\/strong><\/p>\n

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                      Monitorovanie extracelul\u00e1rneho dopam\u00ednu v re\u00e1lnom \u010dase v nucleus accumbens<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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                      Podmienen\u00e1 preferencia miesta<\/span><\/span><\/strong><\/p>\n

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                        Vyhodnotenie potenci\u00e1lu odmeny<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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                        \u0160t\u00fadie termoregul\u00e1cie<\/span><\/span><\/strong><\/p>\n

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                          \u00da\u010dinky na telesn\u00fa teplotu<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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                          Elektrofyziol\u00f3gia<\/span><\/span><\/strong><\/p>\n

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                            Anal\u00fdza vzorcov spa\u013eovania dopam\u00ednov\u00fdch neur\u00f3nov<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

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                            \u010casto kladen\u00e9 ot\u00e1zky<\/span><\/span><\/strong><\/h3>\n

                            Ot\u00e1zka 1: Ak\u00fd je hlavn\u00fd rozdiel medzi 2-FEA a 3-FEA?<\/span><\/span><\/strong>
                            \n A: 2-FEA vykazuje v\u00e4\u010d\u0161ie\u00a0 <\/span><\/span>dopaminergn\u00e1 selektivita<\/span><\/span><\/strong> , zatia\u013e \u010do 3-FEA m\u00e1 silnej\u0161\u00ed\u00a0 <\/span><\/span>serotonergn\u00e9 \u00fa\u010dinky<\/span><\/span><\/strong> \u00a0.<\/span><\/span><\/p>\n

                            Ot\u00e1zka 2: Ako sa t\u00e1to kombin\u00e1cia porovn\u00e1va s 3-FMA?<\/span><\/span><\/strong>
                            \n A: Kombin\u00e1cia 2\/3-FEA m\u00e1\u00a0 <\/span><\/span>miernej\u0161\u00ed profil \u00fa\u010dinku<\/span><\/span><\/strong> \u00a0s ni\u017e\u0161\u00edm neurotoxick\u00fdm potenci\u00e1lom.<\/span><\/span><\/p>\n

                            Ot\u00e1zka 3: Existuje riziko tvorby izom\u00e9rov?<\/span><\/span><\/strong>
                            \n A: Na\u0161e analytick\u00e9 \u00fadaje ukazuj\u00fa, \u017ee\u00a0 <\/span><\/span>\u017eiadne ne\u017eiaduce izom\u00e9ry<\/span><\/span><\/strong> \u00a0sa tvoria pri spr\u00e1vnom skladovan\u00ed.<\/span><\/span><\/p>\n

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                            Pr\u00e1vna pozn\u00e1mka:<\/span><\/span><\/strong>
                            \n Tento produkt spad\u00e1 pod\u00a0 <\/span><\/span>Z\u00e1kon o \u00f3piu<\/span><\/span><\/strong> \u00a0v Holandsku a je\u00a0 <\/span><\/span>ur\u010den\u00e9 v\u00fdlu\u010dne na z\u00e1konn\u00fd vedeck\u00fd v\u00fdskum<\/span><\/span><\/strong> \u00a0s potrebn\u00fdmi povoleniami.<\/span><\/span><\/p>\n

                            Podmienky skladovania:<\/span><\/span><\/strong><\/p>\n

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                              Teplota: 2 \u2013 8 \u00b0C<\/span><\/span><\/p>\n<\/li>\n

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                              Chr\u00e1nen\u00e9 pred vlhkos\u0165ou a svetlom<\/span><\/span><\/p>\n<\/li>\n

                            • \n

                              Skladujte mimo dosahu potrav\u00edn<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                              ","protected":false},"excerpt":{"rendered":"

                              Nahraden\u00e9 peletami Newphoria 2\/3-FEA >><\/span><\/span><\/span><\/span><\/strong><\/span><\/p>","protected":false},"featured_media":27753,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[322,333,324],"product_tag":[326],"class_list":{"0":"post-23587","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-bijna-verboden","7":"product_cat-gefluoreerden","8":"product_cat-pellets-for-pellet","9":"product_tag-nl","11":"first","12":"instock","13":"taxable","14":"shipping-taxable","15":"purchasable","16":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product\/23587","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/comments?post=23587"}],"version-history":[{"count":5,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product\/23587\/revisions"}],"predecessor-version":[{"id":28068,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product\/23587\/revisions\/28068"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/media\/27753"}],"wp:attachment":[{"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/media?parent=23587"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product_brand?post=23587"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product_cat?post=23587"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/sk\/wp-json\/wp\/v2\/product_tag?post=23587"}],"curies":[{"name":"pracovn\u00fd list","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}