4-AcO-MET 20 MG Pellets – Research Substance from the Tryptamine Family

Product Name: 4-AcO-MET (4-Acetoxy-N-ethyl-N-methyltryptamine)
Form: Pressed pellets, 20 mg each
Chemical Class: Psychedelic tryptamine
Molecular Formula: C15H22N2O2
Molecular Mass: 262.35 g/mol
Purity: ≥98% (verified by HPLC and NMR)
Uses: For analytical research and laboratory use only

Description

4-AcO-MET is a semi-synthetic tryptamine structurally related to both psilocin and 4-AcO-DMT. It is often considered a prodrug of MET (N-ethyl-N-methyltryptamine), a substance with serotonergic activity. In research settings, 4-AcO-MET is known for its interesting pharmacological properties and relatively mild, yet significant visual and cognitive effects in experimental models.

The 20 MG Pellets provide standardized and accurate dosing for laboratories analyzing this substance for stability, interaction with serotonin receptors, or structural comparison to related tryptamines.

Applications in Scientific Research

🔬Receptor binding studies (particularly 5-HT2A, 5-HT1A)
🔬Comparative tryptamine research: structural and pharmacological relationships
🔬Visualization of neurobiological processes in animal models
🔬Prodrug analysis and metabolism (from 4-AcO-MET to MET)
🔬LC-MS and GC-MS reference standard for analytical laboratories

Benefits for Researchers

✅ Standardized pellet dosing – Minimizes weighing errors in microdosing experiments
✅ Mild and controllable pharmacological properties
✅ Interesting prodrug structure – Study of metabolism and enzymatic conversion
✅ High purity and stability – Ideal for replication of results

Disadvantages and Possible Limitations

⚠️ Light sensitive – Should be stored in the dark
⚠️ Limited long-term data – Limited clinical literature on toxicological properties
⚠️ Potentially unpredictable effects in animal models at higher doses
⚠️ Not suitable for use outside a controlled research environment

Recommended Laboratory Use

• Starting dose for in vitro testing: 1–5 mg dissolved in ethanol or aqueous buffer
• For binding experiments: 10–20 µM concentration in cell culture medium
• Solubility: Good in ethanol, moderate in water
• Storage: Store in a dry, airtight container and cool (preferably < 8°C).

Laboratory Report – Batch Data

Frequently Asked Questions (FAQ)

❓ Is 4-AcO-MET legal in the Netherlands or Belgium?

➡️The status is a gray area . Not regulated under the Opium Act, but prohibited for human consumption. Permitted only for authorized research.

❓ What is the difference between 4-AcO-MET and 4-AcO-DMT?

➡️4-AcO-MET contains an N-ethyl group instead of a dimethyl group. This may lead to subtly different pharmacological effects, generally with milder visual intensity.

❓ How should I handle the pellets in the lab?

➡️Use gloves and milligram-accurate scales. Wear a lab coat and work under a fume hood when dissolving or handling the material.

❓ Can 4-AcO-MET be stored long-term?

➡️Yes, as long as it’s stored airtight and cool. For optimal stability, store in a dark jar below 8°C.

❓ Is 4-AcO-MET converted to MET in the body?

➡️Animal models have shown that 4-AcO-MET is converted to MET by hydrolysis, making it a prodrug. This makes it interesting for metabolic research.

Warning

⚠️ For use only by qualified researchers in accredited laboratories. Not for consumption, diagnostics, therapeutic use, or household use.