

Tropacocaina HCl
Tropacocaine HCl properties
Sinonimo: NSC 76018
Numero CAS: 637-23-0
Formula: C 15 H 19 NO 2 • HCl
Massa molare: 281.8
Purezza: >98%
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Product Definition: Tropacocaine HCl (Research Chemical)
Chemical Name: Tropacocaine hydrochloride
Synonyms: Tropacocaine HCl, Benzoylecgonine methyl ester
Molecular Formula: C₁₅H₁₉NO₂•HCl
Molecular Weight: 281.78 g/mol
CAS No.: 537-26-8
Appearance: White crystalline powder
Purezza: ≥98% (HPLC verified)
Solubilità: 50 mg/ml in acqua
Description & Pharmacology:
Tropacocaine is a naturally occurring cocaine analog with:
✔Local anesthetic effects
✔Stimulant properties
✔Shorter duration of action than cocaine (1-2 hours)
✔More selective noradrenaline reuptake inhibition
Research applications:
Neuroscience research:
Dopamine transporter studies
Comparative pharmacology of stimulants
Medical examination:
Local anesthetic mechanisms
Vasoconstriction studies
Analytical chemistry:
Reference standard for drug analysis
Forensic investigation
Benefits for Research:
✅ Naturally occurring compound
✅Less addiction potential than cocaine
✅Good stability in solution
✅Suitable for in vitro receptor studies
Risks & Limitations:
❌ Possible side effects:
Tachycardia
Hypertension
CNS stimulation
❌Limited pharmacokinetic data available
❌Potential for abuse
Dosage protocol (for research):
Application | Concentration | Expected effect |
---|---|---|
Studi in vitro | 1-10 μM | legame del recettore |
Local anesthetic test | 0.1-0.5% solution | Nerve block |
Studi sui neurotrasportatori | 5-50 μM | Dopamine/noradrenaline effect |
Safety measures:
Wear appropriate PPE (gloves, lab coat)
Work under a fume hood
Avoid contact with skin and eyes
Do not combine with MAO inhibitors
Frequently Asked Questions:
Is Tropacocaine legal in the Netherlands?
It may fall under the Opium Act as a cocaine-related substance.How is it different from cocaine?
Less euphoric effect, shorter duration of action.Can it be used as a local anesthetic?
For research purposes only, not for medical use.Is it detectable on drug tests?
It may cross-react with cocaine tests.
Quality Control & Analytical Data:
Specifications:
Purity: ≥98% (HPLC)
Heavy metals: <1 ppm
Loss on drying: <0.5%
Residual solvents: <0.1%
Stability data:
Shelf life: 36 months at 15-25°C
Light sensitivity: Moderate
Moisture sensitivity: High
Conclusion:
Tropacocaine HCl is a valuable research substance for pharmacological and analytical studies, but requires responsible use.
⚠ For research purposes only – not for human use
Storage advice:
Airtight packaging
Store in a dark place
Dry at <25°C
Ethical considerations:
For use by qualified personnel only
Animal testing requires ethical approval
Document all experiments accurately
Frequently asked questions
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A seemingly elegant design can quickly begin to bloat with unexpected content or break under the weight of actual activity. Fake data can ensure a nice looking layout but it doesn’t reflect what a living, breathing application must endure. Real data does.
Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.