{"id":23655,"date":"2025-04-13T17:40:11","date_gmt":"2025-04-13T17:40:11","guid":{"rendered":"https:\/\/globalsourcechemicals.com\/?post_type=product&p=23655"},"modified":"2025-10-03T07:20:20","modified_gmt":"2025-10-03T07:20:20","slug":"granules-didra-21-10-mg","status":"publish","type":"product","link":"https:\/\/globalsourcechemicals.com\/fr\/boutique\/idra-21\/granules-didra-21-10-mg\/","title":{"rendered":"IDRA-21 10 mg, granul\u00e9s"},"content":{"rendered":"

Granul\u00e9s IDRA-21 10 mg \u2013 Description scientifique et manuel d'utilisation<\/span><\/span><\/strong><\/h3>\n

Description du produit<\/span><\/span><\/strong><\/h4>\n

IDRA-21 (granul\u00e9s de 10 mg)<\/span><\/span><\/strong> \u00a0est un potentiel\u00a0 <\/span><\/span>Potentiateur du r\u00e9cepteur AMPA<\/span><\/span><\/strong> \u00a0appartenant \u00e0 la classe des\u00a0 <\/span><\/span>produits chimiques de recherche nootropes et neuroprotecteurs<\/span><\/span><\/strong> Il agit en am\u00e9liorant la signalisation induite par le glutamate dans le cerveau, ce qui peut conduire \u00e0 une am\u00e9lioration de la fonction cognitive, de la neuroplasticit\u00e9 et potentiellement de la neuror\u00e9cup\u00e9ration.<\/span><\/span><\/p>\n

Ces granul\u00e9s sont\u00a0 <\/span><\/span>tr\u00e8s pur (\u226598%)<\/span><\/span><\/strong> , dos\u00e9 standardis\u00e9 et destin\u00e9 uniquement \u00e0\u00a0 <\/span><\/span>recherche scientifique et \u00e9tudes pr\u00e9cliniques<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

\n

Utilisations et applications<\/span><\/span><\/strong><\/h3>\n

L'IDRA-21 est \u00e9tudi\u00e9 pour ses effets possibles sur :<\/span><\/span><\/p>\n

    \n
  1. \n

    Am\u00e9lioration cognitive<\/span><\/span><\/strong> \u00a0\u2013 Peut augmenter la vigilance, la capacit\u00e9 d\u2019apprentissage et la consolidation de la m\u00e9moire.<\/span><\/span><\/p>\n<\/li>\n

  2. \n

    Neuroprotection<\/span><\/span><\/strong> \u00a0\u2013 Effet protecteur potentiel dans les maladies neurod\u00e9g\u00e9n\u00e9ratives (par exemple, maladie d\u2019Alzheimer, accident vasculaire c\u00e9r\u00e9bral).<\/span><\/span><\/p>\n<\/li>\n

  3. \n

    R\u00e9cup\u00e9ration neurologique<\/span><\/span><\/strong> \u00a0\u2013 Peut favoriser la plasticit\u00e9 synaptique apr\u00e8s une l\u00e9sion c\u00e9r\u00e9brale.<\/span><\/span><\/p>\n<\/li>\n

  4. \n

    Recherche scientifique<\/span><\/span><\/strong> \u00a0\u2013 Etude de la modulation du r\u00e9cepteur AMPA et de la signalisation du glutamate.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

    \u26a0\u00a0Non approuv\u00e9 pour un usage humain ou v\u00e9t\u00e9rinaire \u2013 R\u00e9serv\u00e9 aux \u00e9tudes pr\u00e9cliniques in vitro et contr\u00f4l\u00e9es.<\/span><\/span><\/strong><\/p>\n

    \n

    Directives posologiques et de s\u00e9curit\u00e9<\/span><\/span><\/strong><\/h3>\n
      \n
    • \n

      Posologie exp\u00e9rimentale (in vitro\/pr\u00e9clinique) : <\/span><\/span><\/strong>\u00a05\u201320 mg\/kg<\/span><\/span><\/strong> \u00a0(selon mod\u00e8le).<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Solution de granul\u00e9s :<\/span><\/span><\/strong> \u00a0Peut \u00eatre dissous dans\u00a0 <\/span><\/span>eau distill\u00e9e ou DMSO<\/span><\/span><\/strong> \u00a0pour des exp\u00e9riences.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Administration:<\/span><\/span><\/strong> \u00a0Par voie orale (mod\u00e8les animaux) ou directement dans les cultures cellulaires.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Fr\u00e9quence:<\/span><\/span><\/strong> \u00a0Dose unique pour effet aigu ; les \u00e9tudes \u00e0 long terme n\u00e9cessitent une surveillance attentive.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

      \ud83d\udea8\u00a0NB:<\/span><\/span><\/strong><\/p>\n

        \n
      • \n

        Aucune application humaine<\/span><\/span><\/strong> \u00a0\u2013 Aucune donn\u00e9e de s\u00e9curit\u00e9 pour l\u2019usage humain.<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Des doses \u00e9lev\u00e9es peuvent provoquer une neuroexcitotoxicit\u00e9.<\/span><\/span><\/strong><\/p>\n<\/li>\n

      • \n

        \u00c9vitez l\u2019association avec d\u2019autres modulateurs du glutamate.<\/span><\/span><\/strong><\/p>\n<\/li>\n<\/ul>\n

        \n

        Inconv\u00e9nients et risques<\/span><\/span><\/strong><\/h3>\n
          \n
        • \n

          Surstimulation des neurones<\/span><\/span><\/strong> \u00a0(risque d'excitotoxicit\u00e9 en cas de surdosage).<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Anxi\u00e9t\u00e9 ou agitation possible<\/span><\/span><\/strong> \u00a0dans les mod\u00e8les sensibles.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Donn\u00e9es \u00e0 long terme limit\u00e9es<\/span><\/span><\/strong> \u00a0sur la tol\u00e9rance et les effets ind\u00e9sirables.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Ne convient pas \u00e0 une utilisation chronique<\/span><\/span><\/strong> \u00a0sans \u00e9tudes approfondies de toxicit\u00e9.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

          \n

          Foire aux questions (FAQ)<\/span><\/span><\/strong><\/h3>\n

          1. L'IDRA-21 est-il l\u00e9gal aux Pays-Bas ?<\/span><\/span><\/strong><\/h4>\n

          Oui, mais seulement pour\u00a0 <\/span><\/span>recherche scientifique<\/span><\/span><\/strong> Il n\u2019est pas soumis \u00e0 la loi sur l\u2019opium, mais il n\u2019est pas non plus approuv\u00e9 comme m\u00e9dicament.<\/span><\/span><\/p>\n

          2. Comment fonctionne exactement IDRA-21 ?<\/span><\/span><\/strong><\/h4>\n

          Il\u00a0 <\/span><\/span>am\u00e9liore la r\u00e9ponse du r\u00e9cepteur AMPA<\/span><\/span><\/strong> , ce qui prolonge et intensifie la signalisation du glutamate. Cela peut am\u00e9liorer la communication synaptique.<\/span><\/span><\/p>\n

          3. L\u2019IDRA-21 peut-il \u00eatre compar\u00e9 \u00e0 d\u2019autres nootropiques ?<\/span><\/span><\/strong><\/h4>\n

          Il a un m\u00e9canisme d\u2019action unique, mais\u00a0 <\/span><\/span>cibles similaires \u00e0 celles des rac\u00e9tams ou des ampakines<\/span><\/span><\/strong> \u00a0(par exemple Sunifiram).<\/span><\/span><\/p>\n

          4. Existe-t-il des interactions connues ?<\/span><\/span><\/strong><\/h4>\n
            \n
          • \n

            Antagonistes du NMDA<\/span><\/span><\/strong> \u00a0(par exemple la m\u00e9mantine) \u2013 Effets potentiellement ind\u00e9sirables.<\/span><\/span><\/p>\n<\/li>\n

          • \n

            Agents GABAergiques<\/span><\/span><\/strong> \u00a0(par exemple, les benzodiaz\u00e9pines) \u2013 Peut r\u00e9duire les effets anxiolytiques.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

            \n

            Rapport de laboratoire et contr\u00f4le qualit\u00e9<\/span><\/span><\/strong><\/h3>\n
              \n
            • \n

              Analyse HPLC : <\/span><\/span><\/strong>\u00a0Puret\u00e9 \u226598%<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Aucun m\u00e9tal lourd ni r\u00e9sidu de solvant d\u00e9tectable<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Formulation homog\u00e8ne de granul\u00e9s<\/span><\/span><\/strong> \u00a0pour un dosage constant.<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Certification des lots<\/span><\/span><\/strong> \u00a0disponible pour les institutions de recherche.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

              \n

              Sc\u00e9narios de recherche recommand\u00e9s<\/span><\/span><\/strong><\/h3>\n
                \n
              1. \n

                \u00e9tudes cognitives<\/span><\/span><\/strong> \u00a0\u2013 Effets sur la m\u00e9moire et l\u2019apprentissage dans les mod\u00e8les animaux.<\/span><\/span><\/p>\n<\/li>\n

              2. \n

                Recherche neuroprotectrice<\/span><\/span><\/strong> \u00a0\u2013 R\u00f4le potentiel dans les l\u00e9sions isch\u00e9miques (mod\u00e8les d\u2019accident vasculaire c\u00e9r\u00e9bral).<\/span><\/span><\/p>\n<\/li>\n

              3. \n

                \u00c9lectrophysiologie<\/span><\/span><\/strong> \u00a0\u2013 Mesures de la r\u00e9ponse du r\u00e9cepteur AMPA dans les cultures neuronales.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                \ud83d\udd2c\u00a0Pour usage contr\u00f4l\u00e9 en laboratoire uniquement \u2013 Pas d\u2019usage r\u00e9cr\u00e9atif !<\/span><\/span><\/strong><\/p>\n

                ","protected":false},"excerpt":{"rendered":"

                Propri\u00e9t\u00e9s des granul\u00e9s IDRA-21<\/span><\/span><\/h3>\n

                Synonyme<\/span><\/span><\/strong> : 7-chloro-3-m\u00e9thyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxyde <\/span><\/span>
                \nCAS <\/span><\/span><\/strong> Nombre<\/span><\/span><\/strong> : 22503-72-6 <\/span><\/span>
                \nFormule<\/span><\/span><\/strong> : C8H9ClN2O2S <\/span><\/span>
                \nMasse molaire<\/span><\/span><\/strong> : 232,6 g\/mol <\/span><\/span>
                \nPuret\u00e9<\/span><\/span><\/strong> : >97%<\/span><\/span><\/p>","protected":false},"featured_media":27900,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[548,549,330,324],"product_tag":[326],"class_list":{"0":"post-23655","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-idra-21","7":"product_cat-idra-21-pellets","8":"product_cat-nootropics","9":"product_cat-pellets-for-pellet","10":"product_tag-nl","12":"first","13":"instock","14":"taxable","15":"shipping-taxable","16":"purchasable","17":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/product\/23655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/comments?post=23655"}],"version-history":[{"count":5,"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/product\/23655\/revisions"}],"predecessor-version":[{"id":28058,"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/product\/23655\/revisions\/28058"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/media\/27900"}],"wp:attachment":[{"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/media?parent=23655"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/product_brand?post=23655"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/product_cat?post=23655"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/fr\/wp-json\/wp\/v2\/product_tag?post=23655"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}