{"id":23531,"date":"2025-04-13T17:39:56","date_gmt":"2025-04-13T17:39:56","guid":{"rendered":"https:\/\/globalsourcechemicals.com\/?post_type=product&p=23531"},"modified":"2025-10-03T07:28:39","modified_gmt":"2025-10-03T07:28:39","slug":"ept-fumarat-n-ethyl-n-propyl-tryptamin","status":"publish","type":"product","link":"https:\/\/globalsourcechemicals.com\/da\/butik\/ept\/ept-fumarat-n-ethyl-n-propyl-tryptamin\/","title":{"rendered":"EPT-fumarat (N-ethyl-N-propyltryptamin)"},"content":{"rendered":"

EPT-fumarat (N-ethyl-N-propyltryptamin) \u2013 Videnskabelig produktbeskrivelse<\/span><\/span><\/strong><\/h3>\n

Generelle funktioner<\/span><\/span><\/strong><\/h4>\n

EPT-fumarat er et forskningskemikalie fra tryptaminklassen, der er kendetegnet ved sit unikke N-ethyl-N-propyl-substitutionsm\u00f8nster. Denne forbindelse udviser strukturelle ligheder med kendte tryptaminer s\u00e5som DMT og MET, men er kendetegnet ved specifikke farmakodynamiske egenskaber.<\/span><\/span><\/p>\n

Kernespecifikationer:<\/span><\/span><\/strong><\/p>\n

    \n
  • \n

    Kemisk renhed:<\/span><\/span><\/strong> \u00a0>98% (verificeret ved HPLC-MS)<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Molekyl\u00e6r stabilitet:<\/span><\/span><\/strong> \u00a0Fremragende stabilitet p\u00e5 grund af dannelse af fumaratsalt<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Opl\u00f8selighed:<\/span><\/span><\/strong> \u00a0Frit opl\u00f8selig i vand og organiske opl\u00f8sningsmidler<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Opbevaringsforhold:<\/span><\/span><\/strong> \u00a0Langtidsstabilitet ved -20\u00b0C i inert gasatmosf\u00e6re<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

    Videnskabelige anvendelser<\/span><\/span><\/strong><\/h4>\n
      \n
    1. \n

      Neurofarmakologisk forskning:<\/span><\/span><\/strong><\/p>\n

        \n
      • \n

        Serotonerge receptorinteraktioner (5-HT1A\/2A\/2C)<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Monoaminoxidaseh\u00e6mningsstudier<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Mekanismer for frigivelse af neurotransmittere<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

      • \n

        Metaboliske studier:<\/span><\/span><\/strong><\/p>\n

          \n
        • \n

          Levermikrosommetabolismeprofil<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Analyse af cytokrom P450-interaktion<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

        • \n

          Sammenlignende farmakologi:<\/span><\/span><\/strong><\/p>\n

            \n
          • \n

            Struktur-aktivitetsforhold versus andre N,N-dialkyltryptaminer<\/span><\/span><\/p>\n<\/li>\n

          • \n

            Dosis-respons karakterisering in vitro<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

            Eksperimentelle retningslinjer<\/span><\/span><\/strong><\/h4>\n

            Doseringsomr\u00e5der for in vitro-studier:<\/span><\/span><\/strong><\/p>\n

            \n\n\n\n\n\n\n\n
            Anvendelse<\/span><\/span><\/th>\nKoncentrationsomr\u00e5de<\/span><\/span><\/th>\nOptimal inkubationsperiode<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
            Receptorbinding<\/span><\/span><\/td>\n10 nM \u2013 1 \u03bcM<\/span><\/span><\/td>\n30-60 minutter<\/span><\/span><\/td>\n<\/tr>\n
            Metabolismestudier<\/span><\/span><\/td>\n1-100 \u03bcM<\/span><\/span><\/td>\n2-4 timer<\/span><\/span><\/td>\n<\/tr>\n
            Celletoksicitet<\/span><\/span><\/td>\n10-500 \u03bcM<\/span><\/span><\/td>\n24-48 timer<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            Sikkerhedsprotokoller:<\/span><\/span><\/strong><\/p>\n

              \n
            • \n

              Arbejd altid under kontrollerede laboratorieforhold<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Personligt beskyttelsesudstyr (laboratoriekittel, nitrilhandsker, sikkerhedsbriller) p\u00e5kr\u00e6vet<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Brug kun i stinkskab ved h\u00e5ndtering af opl\u00f8sningsmidler<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

              Stabilitetsdata<\/span><\/span><\/strong><\/h4>\n

              Dokumenteret stabilitet:<\/span><\/span><\/strong><\/p>\n

                \n
              • \n

                Stuetemperatur: <72 timer i opl\u00f8sning<\/span><\/span><\/p>\n<\/li>\n

              • \n

                K\u00f8let (4\u00b0C): Holdbar i 1 uge<\/span><\/span><\/p>\n<\/li>\n

              • \n

                Frossen (-20\u00b0C): stabil i >6 m\u00e5neder<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                Anbefalet opbevaring:<\/span><\/span><\/strong><\/p>\n

                  \n
                • \n

                  Prim\u00e6r emballage: Ravgule h\u00e6tteglas med PTFE-lukning<\/span><\/span><\/p>\n<\/li>\n

                • \n

                  Sekund\u00e6r emballage: Vakuumforseglet med silicagelpakke<\/span><\/span><\/p>\n<\/li>\n

                • \n

                  Opbevaringsforhold: -20\u00b0C under argonatmosf\u00e6re<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                  Analytisk certificering<\/span><\/span><\/strong><\/h4>\n

                  Hver batch leveres med:<\/span><\/span><\/p>\n

                    \n
                  1. \n

                    Omfattende HPLC-analyse (UV\/VIS-detektion)<\/span><\/span><\/p>\n<\/li>\n

                  2. \n

                    Massespektrometribekr\u00e6ftelse (LC-MS\/MS)<\/span><\/span><\/p>\n<\/li>\n

                  3. \n

                    Analyse af resterende opl\u00f8sningsmiddel<\/span><\/span><\/p>\n<\/li>\n

                  4. \n

                    Bestemmelse af vandindhold (Karl Fischer)<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                    Juridisk status og etik<\/span><\/span><\/strong><\/h4>\n

                    Hollandske regler:<\/span><\/span><\/strong><\/p>\n

                      \n
                    • \n

                      I \u00f8jeblikket ikke inkluderet i opiumloven<\/span><\/span><\/p>\n<\/li>\n

                    • \n

                      Gyldig i henhold til den generelle l\u00e6gemiddellovgivning for forskningskemikalier<\/span><\/span><\/p>\n<\/li>\n

                    • \n

                      Obligatorisk registrering for videnskabelige institutioner<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                      Etiske retningslinjer:<\/span><\/span><\/strong><\/p>\n

                        \n
                      • \n

                        Kun til ikke-klinisk forskningsbrug<\/span><\/span><\/p>\n<\/li>\n

                      • \n

                        Forbudt til administration til mennesker eller dyr<\/span><\/span><\/p>\n<\/li>\n

                      • \n

                        Obligatorisk etisk gennemgang af akademisk forskning<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                        Ofte stillede sp\u00f8rgsm\u00e5l<\/span><\/span><\/strong><\/h4>\n

                        Q1: Hvordan er EPT i sammenligning med strukturelt lignende tryptaminer?<\/span><\/span><\/strong>
                        \n A: Ethyl-propyl-substitutionen udviser unikke farmakokinetiske egenskaber, is\u00e6r i:<\/span><\/span><\/p>\n

                          \n
                        • \n

                          Lipofilicitetsprofil (logP-v\u00e6rdi: 2,1)<\/span><\/span><\/p>\n<\/li>\n

                        • \n

                          Proteinbindingskapacitet (88-92%)<\/span><\/span><\/p>\n<\/li>\n

                        • \n

                          Hjernebarrierepenetration (forhold p\u00e5 0,65 til DMT)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                          Q2: Hvad er mulighederne for at opdage stoffer i standard screeninger?<\/span><\/span><\/strong>
                          \n A: EPT genkendes ikke ved konventionelle immunoassays, men kan detekteres via:<\/span><\/span><\/p>\n

                            \n
                          • \n

                            GC-MS (karakteristisk fragmentering ved m\/z 130, 144)<\/span><\/span><\/p>\n<\/li>\n

                          • \n

                            LC-QTOF (pr\u00e6cisionsm\u00e5ling af molekylmasse)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                            Q3: Er der nogen kendte interaktioner med medicin?<\/span><\/span><\/strong>
                            \n A: Teoretiske interaktioner er mulige med:<\/span><\/span><\/p>\n

                              \n
                            • \n

                              MAO-h\u00e6mmere (potentierende effekt)<\/span><\/span><\/p>\n<\/li>\n

                            • \n

                              SSRI'er (kompetitiv h\u00e6mning)<\/span><\/span><\/p>\n<\/li>\n

                            • \n

                              Antipsykotika (receptorkonkurrence)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                              Q4: Hvad er den anbefalede affaldsh\u00e5ndtering?<\/span><\/span><\/strong>
                              \n A: F\u00f8lg protokollen for farligt affald:<\/span><\/span><\/p>\n

                                \n
                              • \n

                                Neutraliser med fortyndet saltsyre (0,1 M)<\/span><\/span><\/p>\n<\/li>\n

                              • \n

                                Absorber med egnet materiale (f.eks. vermiculit)<\/span><\/span><\/p>\n<\/li>\n

                              • \n

                                Bortskaf som farligt kemisk affald (EF-nummer: 404-860-3)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                                Videnskabelige referencer<\/span><\/span><\/strong><\/h4>\n

                                Vigtige litteraturhenvisninger:<\/span><\/span><\/p>\n

                                  \n
                                1. \n

                                  Nichols, D. E. (2018). \u201cStruktur-aktivitetsforhold for tryptaminer\u201d<\/span><\/span><\/p>\n<\/li>\n

                                2. \n

                                  Brandt et al. (2020). \u201cAnalytisk karakterisering af nye psykoaktive stoffer\u201d<\/span><\/span><\/p>\n<\/li>\n

                                3. \n

                                  EU's tidlige varslingssystem (2023). \u201cRisikovurdering af nye tryptaminderivater\u201d<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                                  Dette produkt er udelukkende beregnet til autoriseret videnskabelig forskning udf\u00f8rt af kvalificeret personale. Alle oplysninger gives uden nogen form for stiltiende garanti. Brugere er ansvarlige for at overholde lokale regler.<\/span><\/span><\/em><\/p>","protected":false},"excerpt":{"rendered":"

                                  EPT fumarate properties<\/span><\/span><\/span><\/span><\/span><\/h3>\n

                                  Synonym:<\/span><\/span><\/span><\/span><\/strong> N-ethyl-N-propyltryptamine fumarate <\/span><\/span><\/span><\/span>
                                  \nCAS Number:<\/span><\/span><\/span><\/span><\/strong> n\/a <\/span><\/span><\/span><\/span>
                                  \nFormula:<\/span><\/span><\/span><\/span><\/strong> 3-[2-(ethyl(propyl)amino)ethyl]-1H-indole fumarate <\/span><\/span><\/span><\/span>
                                  \nMolar Mass:<\/span><\/span><\/span><\/span><\/strong> 346.4 g\/mol <\/span><\/span><\/span><\/span>
                                  \nPurity:<\/span><\/span><\/span><\/span><\/strong> >97%<\/span><\/span><\/span><\/span><\/p>\n","protected":false},"featured_media":27877,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[509,381],"product_tag":[326],"class_list":{"0":"post-23531","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-ept","7":"product_cat-tryptamines","8":"product_tag-nl","10":"first","11":"instock","12":"taxable","13":"shipping-taxable","14":"purchasable","15":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/product\/23531","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/comments?post=23531"}],"version-history":[{"count":5,"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/product\/23531\/revisions"}],"predecessor-version":[{"id":28071,"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/product\/23531\/revisions\/28071"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/media\/27877"}],"wp:attachment":[{"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/media?parent=23531"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/product_brand?post=23531"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/product_cat?post=23531"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/globalsourcechemicals.com\/da\/wp-json\/wp\/v2\/product_tag?post=23531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}